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Fixed-dose combination therapy offers convenient dosing and improves compliance; however, their place in hospice therapy is limited and these novel inhalers are expensive.

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Patients were permitted to use respiratory medications (including short-acting and long-acting beta-agonists, inhaled and systemic steroids, and theophyllines) other than inhaled anticholinergics.

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Tiotropium, when combined with ICS, is superior to doubling the dose of ICS in poorly controlled asthmatics on low-dose ICS, similar to the effect of addition of LABA to ICS.

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These differences have no effect on the medical action of the drug whatsoever.

PEF and pulse oximetry measurements are complementary to history taking and physical examination.

National Asthma Education and Prevention Program and Global Initiative for Asthma guidelines, ICSs are listed as the preferred therapy for asthma inflammation but other considerations, such as allergic disease, adherence, and acceptability, should be considered when individualizing therapy.

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Measurements were recorded daily and analyzed as means of weekly predose values for morning and evening PEF and asthma symptoms.

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We believe that evidence of increased mortality from cardiovascular disease and all cause mortality with the tiotropium Respimat mist inhaler is now so strong that this inhaler should be withdrawn from the market.

Immediate hypersensitivity reactions, including angioedema (including swelling of the lips, tongue, or throat), itching, or rash have been reported.

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This steady state was sustained throughout the treatment period.

To get your full daily dose, you must again, breathe out completely (See Figure N) and for a second time, breathe in (See Figure O) from the same SPIRIVA capsule.

The goal of asthma treatment is to achieve and maintain control.

Common concomitant medications (LABA, ICS) used by patients with COPD were not found to alter the exposure to tiotropium.

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Patients with a low body-mass index or very severe COPD seemed to benefit most from tiotropium therapy ().

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Optimal management of asthma during pregnancy includes objective monitoring of lung function, avoiding or controlling asthma triggers, patient education, and individualized pharmacologic therapy.

Issues specific to geriatric patients that should be included in the decision to prescribe a medication include the presence of comorbidities, life expectancy, redundancies, and the likelihood of compliance.

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Because pneumonia is one of the most common complications of asthma, chest radiography is indicated in patients with fever to rule out pneumonia.

Be careful not to get tiotropium powder in your eyes.

If you are suffering from the disease, hydrate a lot and take loads of bed rest.

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SOURCES: Tumaini R. Coker, assistant professor of pediatrics, Mattel Childrens Hospital and the David Geffen School of Medicine at the University of California at Los Angeles, and researcher, RAND, Santa Monica, Calif.

You should not use the information contained here for diagnosing or treating a health problem or disease.

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Orally inhaled tiotropium bromide antagonizes the muscarinic M(1), M(2), and M(3) receptors located in airway smooth muscle, reversing vagally mediated bronchoconstriction.

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SPIRIVA capsule pieces in the center chamber can cause a SPIRIVA capsule not to rattle.

They have a productive cough and may be cyanotic.

However, some cases resist all conventional modes of therapy.

For example, adequate respiratory therapy has been shown to often be beneficial to ALS patients who suffer from sleep problems.

STIOLTO RESPIMAT contains both tiotropium and olodaterol.

Only 19% of these people, however, were still seeing a doctor, and only 32% used any maintenance medication.

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Other reactions that occurred in the Spiriva Respimat 5 mcg group at an incidence of 1% to 3% and at a higher incidence rate on Spiriva Respimat 5 mcg than on placebo included: Cardiac disorders: palpitations; Gastrointestinal disorders: constipation, gastroesophageal reflux disease, oropharyngeal candidiasis; Nervous system disorders: dizziness; Respiratory system disorders (Upper): dysphonia; Skin and subcutaneous tissue disorders: pruritus, rash; Renal and urinary disorders: urinary tract infection.

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Boys comprised 74 percent of the children, while 75 percent of the adults reporting on their treatment plans were women.

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